Avanafil Information

Buy Avanafil
There is a protein in the body that prevents blood vessels from expanding. Avanafil in essence prevents or blocks this protein so blood vessels can expand. Thus allowing blood to enter the penis and become erect during times of sexual excitement. Its premises is similar to that of vardenafil, sildenafil and tadalafil.
"If things are heated up, theoretically you can get improved function earlier, within 15 minutes, with this drug," said Dr. Irwin Goldstein, director of sexual medicine at Alvarado Hospital in San Diego, and co-author of a recent study about Avanafil in the Journal of Sexual Medicine. "You can argue this is the first potential on-demand drug." The "on-demand" drug could end up in high demand for men with ED who do not respond to drugs like Sildenafil, Tadalafil and Vardenafil.
Avanafil Dosage
The recommended starting dose is 100 mg. Avanafil ought to be taken orally as required approximately thirty minutes before sexual acts. Based upon individual efficacy and tolerability, the dose could possibly be increased into a maximum dose of 200 mg or decreased to 50 mg. The best dose that provides benefit really should be used. The most recommended dosing frequency is once daily. Sexual stimulation is essential for just a respond to treatment.


Avanafil (Stendra™)

Avanafil occurs as white crystalline powder, molecular formula C23H26ClN7O3 and molecular weight of 483.95 and is slightly soluble in ethanol, practically insoluble in water, soluble in 0.1 mol/L hydrochloric acid. For oral administration, is supplied tablets containing 50 mg, 100 mg, or 200 mg avanafil debossed with dosage strengths. In addition to the active ingredient, each tablet contains the following inactive ingredients: mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate, and ferric oxide yellow. Avanafil is a selective inhibitor of cGMP-specific PDE5, is designated chemically as (S)-4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2- pyrimidinylmethyl)-5-pyrimidinecarboxamide.


Single doses up to 800 mg have been given to healthy subjects, and multiple doses up to 300 mg have been given to patients. In cases of overdose, standard supportive measures should be adopted as required. Renal dialysis is not expected to accelerate clearance because avanafil is highly bound to plasma proteins and is not significantly eliminated in the urine.

Other Requirements

  • Store Avanafil at 68°F to 77°F (20°C to 25°C).
  • Keep Avanafil out of the light.
  • Keep Avanafil and all medicines out of the reach of children.

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